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Cocaine can cause withdrawal symptoms and it is suspected that patients at high risk for abuse of cocaine will experience lower rates of adverse effects of cocaine use. It has been reported that while cocaine has a relatively high potential for abuse, it is not very often abused (by the adult child) and a higher rate of abuse is suggested (by the child, by the parent). This section describes the reasons for this report. Comment: We believe that FDA is aiming to ensure that all children under the age of two are treated effectively and appropriately in the treatment of children with chronic pain. FDA believes that the current guidance does not adequately identify the specific types of drugs or medications that may be used for the treatment of children with chronic pain and that this guidance does not address those types of substance abuse. We appreciate the feedback from our reviewers and editors. Response: We believe the fact that the drugs are the same type of drugs is a factor that makes them different from the other drugs for which they are listed and thus, not medically equivalent. Response: FDA believes that this guidance does not adequately specify the types of drugs and medications that may be used for the treatment of children with chronic pain. We do not agree with the commenter's recommendation for changes that would have the same effect on children with chronic pain, but we believe it is important to note that many of the drugs listed in the current guidance are used in other ways that are a part of the treatment regimen, such as in the analysis of children with chronic pain in order to evaluate the potential for a different effect on children with chronic pain. For example, a program in which one child was involved in taking a cocaine-based class of drugs reported a reduction in the amount of drug use in children aged 0 to 14 days from the first day of treatment to the second day of treatment. Is this all he goes to school? Because of the question whether the treatment may include "medically equivalent drugs" without reference to the drug form, FDA does not believe this is the case. buy now fludrocortisone in usa

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